A PubMed vocabulary is a domain-specific set of words and subword tokens derived directly from biomedical literature in the PubMed database for use in natural language processing models. Unlike general-purpose vocabularies compiled from standard web text or literature, a PubMed vocabulary is tailored to capture complex medical, biological, and pharmacological terminology as distinct lexical units. Constructing a tokenizer vocabulary directly from biomedical text prevents specialized concepts, gene names, and clinical terms from being fragmented into generic or arbitrary subword pieces, thereby optimizing token efficiency and improving the ability of language models to comprehend and process scientific text.