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Christensen algorithm
The Christensen algorithm is a non-rigid image registration method that aligns complex, large-deformation medical images by modeling the transformation field as a continuous viscous fluid flow. Developed in computational anatomy for mapping subject anatomies to standardized atlases, the algorithm generates smooth, topology-preserving, and invertible mappings between images by allowing accumulated internal strain to relax over time rather than building restorative elastic resistance. In this framework, deformation forces derived from image intensity differences drive a linear Navier-Stokes fluid differential operator to determine instantaneous velocity fields. The algorithm also integrates iterative regridding or step-size constraints to ensure the mapping maintains a positive Jacobian determinant, preventing structural tearing or grid folding during extensive anatomical deformations.
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